The shift to Alternative Methods creates significant challenges in the fragrance industry. The loss of key tools in the risk assessment process complicates our ability to successfully address the questions on safety. The need for validated and accepted experimental tests is essential to answering these challenges. Our task is to identify suitable alternatives and determine how best to integrate them into the process.
The shift to alternatives-what are the specific consideration for fragrance materials?
Is the test system compatible/adaptable to our materials?
Concerns with solubility or volatility
Is the test system relevant to fragrance exposure?
Dermal and inhalation
Is the test system useful for complex mixtures?
RIFM Bulletin on Alternative Methodologies for Fragrance Safety Testing
|A Screening-Level Environmental Assessment of Macrocyclic Fragrance Materials|